Announcement

Collapse
No announcement yet.

crestor

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • crestor

    Why is crestor started at a low dose for those of asian origins?

  • #2
    Re: crestor

    Because the genetic make-up of patients of Asian origins is different from that of Caucasian patients, and this leads to higher plasma levels in Asian patients:
    "Race: Pharmacokinetic studies show an approximate 2-fold elevation in median AUC and Cmax in Asian subjects (Japanese, Chinese, Filipino, Vietnamese and Koreans) compared with Caucasians; Asian-Indians show an approximate 1.3-fold elevation in median AUC and Cmax. A population pharmacokinetic analysis revealed no clinically relevant differences in pharmacokinetics between Caucasian and Black groups. ", says the SPC .
    Ze genuine Article, present & perfect!

    Comment

    Working...
    X