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preservitives in eye drops

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  • preservitives in eye drops

    Right, dexamethasone 0.1% minims preservative free are problem getting a hold of at the minute.

    Would the maxidex(dexamethasone 0.1%) 10ml multi-dose drops that contain preservatives cause any problems.

    Was prescribed for a cornea transplant.

    Why prescribe preservative free in the first place, is it because the preservatives can cause irritation or is there another more important reason?

  • #2
    Re: preservitives in eye drops

    Some people are allergic to the preservatives used. We have a few regulars who we have to get the p/f version for. One of them told me that it caused her intense irritation.

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    • #3
      Re: preservitives in eye drops

      is this standard practice in all patients that have cornea transplants to give preservative free drops just incase they might get an irritation?
      Last edited by Mr Pharm S; 9, December 2008, 12:22 PM. Reason: bad bad grammer

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      • #4
        Re: preservitives in eye drops

        Don't know about that, but a Specials Lab should be able to knock you some out (for an absurd price, natch)

        Moorfields eye Hospital should be able to advise further, I've always found them very good!

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        • #5
          Re: preservitives in eye drops

          Originally posted by Pharmabob View Post
          ................., but a Specials Lab should be able to knock you some out (for an absurd price, natch)
          Not absurb if they give you a 50% rebate!!!

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          • #6
            Re: preservitives in eye drops

            Originally posted by Pharmabob View Post
            Don't know about that, but a Specials Lab should be able to knock you some out (for an absurd price, natch)

            Moorfields eye Hospital should be able to advise further, I've always found them very good!
            moorfields can get hold of almost anything you can put into your eye but beware! A lot of their products have a seven day expiry.
            We recently went through a rigmarole with a patient needing atropine eye drops - on long term mcs. They have motor problems so couldn't use the p/f version in udv form.
            After a bit of chasing round moorfields gave us a quote of around £90 for a bottle. Which only lasted seven days. Working out to £360 worth of drops per month.
            Once we let the surgery know about this they arranged a district nurse to call daily to administer the udv eye drops until a social care company can take over the role.
            “It's not worth doing something unless you were doing something that someone, somewhere, would much rather you weren't doing.”

            Terry Pratchett

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            • #7
              Re: preservitives in eye drops

              Yeah we get them made up quite often from our specials company, the problem I had last week was it takes 5 working days and the chap was going away for christmas before they'd be delivered.

              Got me thinking about why they would prescribe preserv free, do the preserv's affect the transplant?

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              • #8
                Re: preservitives in eye drops

                Moorfields have their own supply of Dexamethasone 0.1% preservative free which they receive from Moorfields Pharmaceutics.

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                • #9
                  Re: preservitives in eye drops

                  In the old days, Phenylmercuric nitrate/acetate was standard. Still used in Chloramphenicol. However, Mercury salts have many effects on nervous system. Also blamed for 'grey baby' syndrome in neonates.
                  This was originally due to calomel in teething powders. Change made to hydroxybenzoates and these have become the norm.
                  johnep

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