Hi,
I'm hoping some of you chemists can help me.
What i'm after is do you know of any inactive substances in humans that i can use as a placebo alongside NaHCO3 (Sodium bicarbonate)?
I'm investigating serial NaHCO3 supplementation on sporting performance and am asking my subjects to consume fairly large amounts of NaHCO3 (eg for 80kg male largest dose will be 48g, spread over 4 smaller 12g doses over the day). Originally i was going to use CaCO3, but subjects won't be able to consume anywhere near enough of this to be a credible placebo, therefore i need another compound.
I spoke to a chemist at boots and he recommended using lactose, but isn't that a sugar and so the extra carbohydrate may affect performance?
Or cellulose, or something like "crystallised cellulose", but there seems to be many different types (eg methyl, ethyl....), and saw that some turn water into a gel and so again that type won't work. Is there a form of cellulose i can use that looks like a white powder and acts similar to NaHCO3 in water?? I'm going to mask the taste's with a flavoured powder.
Which would you use?
Hopefully somebody can help.
I'm hoping some of you chemists can help me.
What i'm after is do you know of any inactive substances in humans that i can use as a placebo alongside NaHCO3 (Sodium bicarbonate)?
I'm investigating serial NaHCO3 supplementation on sporting performance and am asking my subjects to consume fairly large amounts of NaHCO3 (eg for 80kg male largest dose will be 48g, spread over 4 smaller 12g doses over the day). Originally i was going to use CaCO3, but subjects won't be able to consume anywhere near enough of this to be a credible placebo, therefore i need another compound.
I spoke to a chemist at boots and he recommended using lactose, but isn't that a sugar and so the extra carbohydrate may affect performance?
Or cellulose, or something like "crystallised cellulose", but there seems to be many different types (eg methyl, ethyl....), and saw that some turn water into a gel and so again that type won't work. Is there a form of cellulose i can use that looks like a white powder and acts similar to NaHCO3 in water?? I'm going to mask the taste's with a flavoured powder.
Which would you use?
Hopefully somebody can help.
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