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Vitamin K injection dilution

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  • Vitamin K injection dilution

    I read that if IV infusion of vitamin K is to be administered to neonates, it should be diluted with preservative free D5W or WFI. What's the rationale of using preservative free diluent? Does it apply for IV infusion of vitamin K for infants or children? By the way, is using injection vitamin K for oral extemporaneous preparation a common practice in any of ur institution and has its safety been proven? tq

  • #2
    Re: Vitamin K injection dilution

    generally, preservatives should be avoided in injections as much as possible.
    multi dose vials will need one, but not single use ampoules.

    As a rep I used to promote Konakion paediatric capsules for neonates.... was over 40 years ago.
    johnep

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    • #3
      Re: Vitamin K injection dilution

      Konakion MM paediatric is licensed for IV/IM/PO use while 'regular' Konakion MM is only licensed for IV/IM use. They are however as far as i know exactly the same preparation, the only difference being the amount in the ampoule.

      We quite commonly use the 'regular' preparation orally, but it does taste really disgusting!!!!!!

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      • #4
        Re: Vitamin K injection dilution

        Originally posted by ykw View Post
        I read that if IV infusion of vitamin K is to be administered to neonates, it should be diluted with preservative free D5W or WFI. What's the rationale of using preservative free diluent? Does it apply for IV infusion of vitamin K for infants or children? By the way, is using injection vitamin K for oral extemporaneous preparation a common practice in any of ur institution and has its safety been proven? tq
        Yes, given orally into the mouth is common--konakion comes with oral dosage droppers in the box.

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        • #5
          Re: Vitamin K injection dilution

          thanks, everybody, for the replies.

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