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Thread: Can someone help me with this radiochemistry question please?

  1. #1
    shenzys is offline Frequent Poster
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    Can someone help me with this radiochemistry question please?

    So the question is:

    Calculate the radioactive concentration (MBq/ml) of a sodium pertechnetate [99mTC] solution with a concentration of 2.0 * 10^-6 g/L.

    Mr (sodium pertechnetate) = 186
    half life of [99mTc) = 6.02 hours
    Avagadro's constant = 6.02 * 10^23

    Okay, so the first step would be to work out the decay constant (lamda) from the half life which I can do but, after that I kind of get stuck. Do I need to calculate the activity (A) by using the formula A= lamda N?
    How do I work out N if I don't have the mass to work out the moles of the compound? And then how does that enable me to work out the concentration using c=n/v without a volume

    Also, am I going about the question the correct way?

  2. #2
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    Pharmanaut is offline Newly registered in 1981
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    Re: Can someone help me with this radiochemistry question please?

    Quote Originally Posted by shenzys View Post
    So the question is:

    Calculate the radioactive concentration (MBq/ml) of a sodium pertechnetate [99mTC] solution with a concentration of 2.0 * 10^-6 g/L.

    Mr (sodium pertechnetate) = 186
    half life of [99mTc) = 6.02 hours
    Avagadro's constant = 6.02 * 10^23

    Okay, so the first step would be to work out the decay constant (lamda) from the half life which I can do but, after that I kind of get stuck. Do I need to calculate the activity (A) by using the formula A= lamda N?
    How do I work out N if I don't have the mass to work out the moles of the compound? And then how does that enable me to work out the concentration using c=n/v without a volume

    Also, am I going about the question the correct way?
    Its years since I last worked out one of these.
    Have a think about the concentration.
    "solution with a concentration of 2.0 * 10^-6 g/L."
    Gives you the mass per litre, just assume you are playing with a litre of the stuff.
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  3. #3
    Nik's Avatar
    Nik
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    Re: Can someone help me with this radiochemistry question please?

    Quote Originally Posted by shenzys View Post
    So the question is:

    Calculate the radioactive concentration (MBq/ml) of a sodium pertechnetate [99mTC] solution with a concentration of 2.0 * 10^-6 g/L.

    Mr (sodium pertechnetate) = 186
    half life of [99mTc) = 6.02 hours
    Avagadro's constant = 6.02 * 10^23

    Okay, so the first step would be to work out the decay constant (lamda) from the half life which I can do but, after that I kind of get stuck. Do I need to calculate the activity (A) by using the formula A= lamda N?
    How do I work out N if I don't have the mass to work out the moles of the compound? And then how does that enable me to work out the concentration using c=n/v without a volume

    Also, am I going about the question the correct way?
    Radiopharmacy is interesting but I'm useless at physics so I don't know the correct method. However I can give you a tip - you are given mass if I'm not mistaken, as you quoted conc = 2x10^-6g/L. Easy peasy stuff to start: use equation no of moles = mass/Mr to get N.
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