useless rubbish..

[pharout]

Point well taken, however sometimes meds are taken on a full stomach to avoid GI side effects and antacids are avoided with meds that they may chelate with to decrease their absorption. I make up that most pharmacists remember this by drug vs. what the pH is relative to the drug.

[shaggy-dog]

I didn't either, until after 11 years of being a regular pharmacist I saw the light and went into industry. Suddenly, the relevancy of all the stuff I hated about my undergraduate training came sharply into focus.
Interestingly, I deal a lot of the time with dental scientists and the relationship between pH and buffering foxes a lot of them - and they have to understand enamel erosion, and this is nigh impossible if you don't know basic physical chemistry.

[Pharmanaut]

Originally Posted by silnarnin

You don't understand the importance of pH to pharmacy?

So how do you know if a medicine should taken in a empty stomach or full stomach, or avoid antacids?! It's all about the pH. The pH in which the coating of the tablets dissolve, or the pH where the own drug dissolves! By the way, if a drug isn't dissolved, it can't be absorbed!

How do you think the enteric coating of tablets works? It's the pH!

Ketoconazole + Omeprazole.
pH dependant drug interaction If I remember correctly.

[kemzero]

Originally Posted by pharout

Point well taken, however sometimes meds are taken on a full stomach to avoid GI side effects and antacids are avoided with meds that they may chelate with to decrease their absorption. I make up that most pharmacists remember this by drug vs. what the pH is relative to the drug.

Tetracycline /Oxytetracycline chelates with milk, and the chelated product gets deposited in bones/teeth etc undergarduate pharmacology, but useful when giving advise to patients particularly growing children!

Knowledge is power !..... "useless rubibish" is always stored in your hind brain when you don't need it, but one day you might need it and all you need to do is thiiiiiiiiinnnnnkkkk deeply and ....voila!

Anyone enjoyed stereochemistry at Uni?

[Pharmanaut]

Originally Posted by kemzero

Tetracycline /Oxytetracycline chelates with milk, and the chelated product gets deposited in bones/teeth etc undergarduate pharmacology, but useful when giving advise to patients particularly growing children!

Knowledge is power !..... "useless rubibish" is always stored in your hind brain when you don't need it, but one day you might need it and all you need to do is thiiiiiiiiinnnnnkkkk deeply and ....voila!

Anyone enjoyed stereochemistry at Uni?

We used to have a patient with tetracycline teeth. They used to get free veneers.
Anyway, all this stuff comes in handy when watching CSI. You can solve it half way through, so you don't have to watch it all.

[Asterix]

I am thinking of doing a couple of days work exp in hospital setting. done community twice now and I find it so boring, the pharmacist just seems to look at prescriptions and phone people...too harsh?

[kemzero]

Originally Posted by giggsy

I am thinking of doing a couple of days work exp in hospital setting. done community twice now and I find it so boring, the pharmacist just seems to look at prescriptions and phone people...too harsh?

I presume thats what is known as prescription intervention!