what do you do if you instead of me ?

[mohamed mostafa]

In this matter we will discus the prescription errors which met us in the pharmacy, and putting the suggestions and solutions to correct these errors
let,s start with example :

patient came to me with prescription of these drugs
1-plavix 75 mg ( clopidogrel )
2-omeprazole 20 mg

what do you do if you instead of me ? will you give the midicine to the patient or not ? and why ?
waiting..........

[Web Ferret]

Depends, has patient has this combination before?

If patient is on a PPI then aspirin for anti-platelet use is not suitable either so clopidogrel being used I assume.

BNF doesn't list an interaction between clopidogrel & PPIs.
MHRA has "Reduced effect of clopidogrel - concomitant use not recommended unless considered essential"
Not a safety issue that I can see if patient is not on any other medicines.

[evilmonkey]

See point 7 of the Q&A section
Safety warnings and messages for medicines : MHRA

[mohamed mostafa]

See point 7 of the Q&A section
Safety warnings and messages for medicines : MHRA

useful informations evilmonkey ,

Based on this reduced effect of clopidogrel and the patient is vulnerable to danger , so in this case i have to ask the doctor befor i do anything ! ( just an opinion )

[jamesbt]

We would now ask the Dr to substitute the omeprazole for ranitidine, which is a safer option interaction wise.
J

[angeldelight]

Ranitidine has lot of interactions though... so if the person had no other meds it might be ok but a lot of people on clopidogrel are on other drugs. Pantoprazole is a PPI which can be used