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Thread: betahistidine

  1. #1
    boycie is offline Frequent Poster
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    betahistidine

    How long does it take to work? Is it only prescribed for Meiner disease or even for usually vertigo?

  2. #2
    Nik's Avatar
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    Re: betahistidine

    It is licensed for use in Meniere's as a prophylactic agent against recurrent attacks of vertigo or tinnitus or hearing loss. In an acute attack, prochlorperazine or an anti-histamine is used (for nausea/vomiting and vertigo).
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    boycie is offline Frequent Poster
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    Re: betahistidine

    And do you know how many days it needs to work?

    thx

  4. #4
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    Re: betahistidine

    No idea I'm afraid - there must be a pharmacology textbook with the answer.
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    Re: betahistidine

    Quote Originally Posted by Nik View Post
    No idea I'm afraid - there must be a pharmacology textbook with the answer.
    I don't think it's clear whether betahistine even works at all. It's certainly not a well proven drug.

  6. #6
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    Re: betahistidine

    You're right, and it is a bit of a strange drug. Evidence is a bit conflicting to say the least:

    NHS Clinical Knowledge Summaries - Clinical topic - Meniere's disease...Preventing recurrent attacks
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    Re: betahistidine

    Quote Originally Posted by Nik View Post
    You're right, and it is a bit of a strange drug. Evidence is a bit conflicting to say the least:

    NHS Clinical Knowledge Summaries - Clinical topic - Meniere's disease...Preventing recurrent attacks
    In some countries (eg. the US), betahistine is not marketed. I suspect it wouldn't be approved in the UK either if it hadn't already been available since the year dot.

    GPs seem to use it a lot around here for a wide variety of different forms of vertigo/dizziness; I don't think this use is justified. They would probably be better off using something else. I suppose betahistine has the advantage of not causing many adverse effects. Sounds like a placebo!

  8. #8
    hibernia is offline King Amongst Members
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    Re: betahistidine

    Quote Originally Posted by bobbin View Post
    GPs seem to use it a lot around here for a wide variety of different forms of vertigo/dizziness; I don't think this use is justified.
    Same on this side of the Irish Sea. It tends to be used when they don't know what to do with the patient - when they aren't bad enough to refer to hospital but they have to give them something.
    I've been dispensing a lot of it for two decades and have yet to see any dramatic results with it.

  9. #9
    Kareempharmacist is offline Junior Member
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    Re: betahistidine

    Betahistine is approved in the uk and is available in the bnf:British National Formulary
    It takes about one week to be able to stop the vertigo attacks .Its effect appears gradually..

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