And how exactly would you do this ?? And besides you can't reproduce human gestation in animal models. Agomelatine is obviously going to go throguh clinical testing in humans because it is an anti-depressant ! Prescribing is never a simple, black and white process - antidepressants generally have an unfavourable record in adolescents, so should you not be relieved that your GP is "erring on the side of caution" by not prescribing it ?



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. If you're options are exhausted then other things will need to be considered, but just because a new medicine is available does not mean it should automatically be prescribed. Clinical trials cannot test for long term safety and are not robust enough to determine the place of a new drug in therapy - i'd agree that some doctors would want to consider a new drug if other things have been tried but it is much better (and safer) to let those experienced in that field to start the ball rolling before it is routinely prescribed in primary care.
