Thiazides

[nenah]

i have searched everywhere for this

i would like to know why thiazides are the firstline treatment for hypertension in african american people. sorry if to some people this might seem like a stupid question
thanks

[johnep]

Thiazides are generally 1st line for all.
In UK bendrofluazide 2.5mg
in US hydrochlorothiazide 25-50mg.
johnep

[nenah]

oh ok

so what i heard about it being the firstline treatment for black people is wrong? or did i get the drug wrong?

[laurabuk]

Hi Nenah,

According to NICE - either a thiazide diuretic or a calcium-channel blocker is the first line for black patients of any age (of African or Carribean descent) or other patients above the age of 55.

We were told that this is because these patients do not respond to ACE-Inhibitor monotherapy as well as younger patients of non-African or Carribean descent.

Hope that answers your question