Initial aggravation of anxiety is common when starting SSRIs, although they are frequently useful in the treament of anxiety disorders in the long-term. Less commonly, agitation and physical restlessness can occur. Some patients have a manic-type reaction eg. racing thoughts, pressured speech, excitation, overactivity, reduced need for sleep and profound changes in mood. Hallucinations and psychotic symptoms occur rarely. Manic reactions are much more common in patients who suffer from bipolar disorder.


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