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Thread: Ranolazine

  1. #1
    Pharmacie's Avatar
    Pharmacie is offline Active Member
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    Ranolazine

    While I was studying Angina, I saw the traditional anti-anginal drugs NTG , BB or CCB.
    But I encounterd a new drug that is Ranolazine.

    Have anyone encoutered Ranolazine in his/her practical experience?

  2. #2
    Nik's Avatar
    Nik
    Nik is offline Keep it surreal
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    Re: Ranolazine

    Our trust has it in stock but I suspect it's not on the formulary. More info:

    http://www.clinicalpharmacy.org.uk/f...calupdate2.pdf
    http://i620.photobucket.com/albums/t...snroses2-1.jpg

    ”We are real. We are not glam sh*t or anything else. We are Guns N’ Roses.”

  3. #3
    laurabuk is offline Prolific Poster
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    Re: Ranolazine

    Our cardiologists are loving it at the moment. It's now on formularly alongside other new additions ivabdradine, eplerenone and dronedarone.

  4. #4
    bolam is offline Loyal Member
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    Re: Ranolazine

    i though ranolazine was used as a protective measurement in ischaemic heart disease, as it prevents cell death via preventing calcium overload

  5. #5
    Pharmacie's Avatar
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    Re: Ranolazine

    Unlike other anti-anginal drugs (BB,NTG,CCB), ranolazine dosn't affect heart rate , contractility , vascular resistance or coronary blood supply!
    It just inhibits late Na current.

  6. #6
    bolam is offline Loyal Member
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    Re: Ranolazine

    thats right, it blocks the slow persistant na channel in the heart which is opened due to hypoxia

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