glaucoma and muscarinic drugs e.g carbachol/pilocarpine

[bolam]

I have the worst brain for picturing things but I dont see how muscarinic agonists help with the treatment of glaucoma. Muscarinic agonists cause the lens in the eye to become more concave and fat and move closer to the iris. In my opinion this should block drainage of aqueous humour rather then help it?
maybe its just late and my brain isnt functioning but i cant see it...

[johnep]

but i cant see it

Perhaps you need your eyes testing.
johnep

[Nik]

The way the cholinergics work is to increase aqueous humour outflow by stimulating ciliary muscle contraction and thus allowing outflow through the trabecular meshwork.
Contraction of ciliary muscle pulls the ciliary body forwards and inwards allowing the lens to bulge more (ie it becomes CONVEX).