calcitriol capsule

[ykw]

i heard in places where the liquid form of calcitriol is not available, the calcitriol capsules are poked using a needle and its content(sort of oily liquid) being drawn out. is this a common practice, or, is it safe to do so? perhaps alfacalcidol drop will be a better choice?

[johnep]

Calcitripl is the di hydroxylated form whereas alphacalcidol is one hydroxyl.

Vit D is inactive in the body until hydroxylated in the liver and kidney. Kidney failure or anephric pts cannot do this but even if only 10% of liver left, hydroxylation is possible. Main point is that calcitriol double price of one alpha.
johnep

[ykw]

Is it safe to do what i mentioned to the calcitriol capsule, which is to draw out its content by using a syringe and needle? thanks

[johnep]

OK for oral, would not consider for injection.
johnep