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Old 22nd, January 2008, 08:33 PM
mr_colt mr_colt is offline
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Join Date: Dec 2006
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Default Re: Cytochrome P450 2D6 (CYP2D6) testing

I see what you are saying but;

I don't know any clinical chemists and I have exhaustively searched the net but all the sites of interest are in other countries. I was just hoping someone on here might know where to point me to.

Or were you talking about the relevance between CYP2D6 and metabolism of codeine etc? From what I understand; CYP2D6 strips the methyl group off about 10% of the methylmorphine (codeine) turning it into morphine. Obviously people defficient in this enzyme will get little or no analgesic effect. Apparently it is required to properly metabolise a large number of drugs.

More information can be found here: CYP2D6 - Wikipedia, the free encyclopedia (yes i know its a wiki article but appears to be accurate.)

mr_colt.

Last edited by mr_colt; 22nd, January 2008 at 10:21 PM.
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