Re: Digoxin
Yep - a longer quote from the wiki link I gave in my first reply.
"In clinical practice, this means that it takes just over 4.7 times the half-life for a drug's serum concentration to reach steady state after regular dosing is started, stopped, or the dose changed. So, for example, digoxin has a half-life (or t½) of 24-36 hours; this means that a change in the dose will take the best part of a week to take full effect."
So 4.7 x 1 (day if 24 hour half life) = 4.7 days
or 4.7 x 1.5 days (if a 36 hour half life) = 7 days
Jeff
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