Quote:
Originally Posted by jeffradd  how many days should i consider 125mcg PO QD to reach its steady state? |
Biological half-life - Wikipedia, the free encyclopedia
"So, for example, digoxin has a half-life (or t½) of 24-36 hours; this means that a change in the dose will take the best part of a week to take full effect"
However I can't see a reason for taking digoxin 125mcg QD rather than 500mcg as a daily dose - but that's just intuition - I haven't gone through the maths.
Is the intention to reach a steady state or to establish a clinical effective more quickly and then reduce the dose?
Jeff