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thanks for the response,

I am having a bit of a debate with another person on this one, its a bit like talking to a brick wall sadly. I did some research on it and I was fairly sure that a high metabolism as he was suggesting it would have no real effect.

So far as I understood the drugs will go through something called 1st pass metabolism and that the drugs themselves are metabolised in the liver.

I think the confusion is coming from the word metabolism, in that drug metabolism and general metabolism as joe public thinks of it are two distinclty different things....

edit: for instance would this statement he made hold truein relation to pharmaceuticals? " the breakdown and carrying of ANY compound and its time cycle in the body is determined directly by the metabolic rate"