certainly makes me upset to see such commend.

i had done reading on it and want to confirm its usage. JNC VII gulideline stated ACEi use in controlling HPT in the compelling indication of chronic renal failure. however, ACEi has harmful effects towards the kidney. the practice sometimes is that when the patient's renal function further deterioated or approaching end stage, doctors will stop ACEi or not use ACEi on CRF patients. is it that: should creatinine clearance decreases 20-30% or hyperkalemia develop, treatment with ACEi is to be stopped? thanks