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Old 26th, February 2006, 09:49 PM
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Default I found this

"As a maintenance agent for opioid dependency, buprenorphine offers advantages such as a lower level of dependence and minimal withdrawal symptoms, due to its partial agonist properties at the micro-opioid receptor. Previous studies have shown 8 mg sublingual buprenorphine to be equivalent to 60 mg oral methadone in terms of retention rate and opioid-negative urine levels. "

I think the partial agonist property of buprenorphine can put a client into bad withdrawel symptoms, and is why they wait until they are on a much lower dose of methadone before starting Subutex.

I found this on the net. Try this link as well: -

http://opioids.com/buprenorphine/bupvmeth.html

Hope it helps
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